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A Breakthrough Treatment for Treatment-Resistant Depression

At Illumma, we are dedicated to providing innovative and science-backed treatments to help individuals struggling with mental health challenges. We are proud to offer Spravato (esketamine) therapy, an FDA-approved nasal spray treatment for adults with treatment-resistant depression (TRD) and major depressive disorder with suicidal ideation (MDSI).

Unlike traditional antidepressants that can take weeks or months to take effect, Spravato works rapidly, offering relief within hours or days. If you have tried at least two antidepressant medications without success, Spravato may be the breakthrough treatment you’ve been searching for.

Spravato

What is Spravato?

Spravato (esketamine) is a prescription nasal spray derived from ketamine, a well-known anesthetic and mental health treatment. It targets the NMDA receptors in the brain, promoting neuroplasticity and enhancing mood regulation in ways that traditional antidepressants cannot. This unique mechanism makes Spravato one of the most effective and fastest-acting depression treatments available.

Spravato is approved by the U.S. Food and Drug Administration (FDA) for adults who:

How Spravato Works

Unlike conventional antidepressants that primarily target serotonin and other neurotransmitters, Spravato stimulates the glutamate system, which plays a crucial role in mood regulation and cognitive function.

Benefits of Spravato Therapy at Illumma:

What to Expect During Spravato Treatment at Illumma

Spravato is administered in-office under medical supervision and requires a minimum two-hour observation period after each dose to ensure safety. Here’s what to expect:

1. Initial Consultation

Before starting treatment, you will meet with an Illumma medical provider for a comprehensive evaluation to determine if Spravato is right for you. Our team will review your medical history, current medications, and previous treatments.

2. In-Clinic Treatment Sessions

3. Ongoing Treatment & Monitoring

  • Weeks 1-4: Twice per week
  • Weeks 5-8: Once per week
  • After 8 weeks: Maintenance sessions as needed, typically 2-4 times per month based on need.
woman wearing eyemask receiving a ketamine spravato treatment at Illumma

What Makes Illumma Different?

Get Better Results at Illumma

We have helped over 1,200 clients in the last 6+ years, making us one of the most experienced clinics in Austin. We understand the healing process of ketamine on a deeper level and have the highest trained staff in the field. We bring the same intentionality and client-focused care we have optimized for ketamine therapy to our Spravato treatments.

Exclusive Benefits at Illumma:

Austin’s Best-Reviewed Ketamine Clinic

We are Austin’s top-reviewed ketamine clinic for a reason. Illumma is a mission-driven clinic deeply committed to supporting your healing journey. We truly care about our clients and work tirelessly to provide transformational and compassionate care. Read our Google Reviews.

Insurance & Pricing

With Insurance

Illumma is committed to making Spravato treatment accessible. We are in-network with the following insurance providers:

Without Insurance

If you are paying out of pocket, pricing is as follows:

Financial assistance may be available through Janssen Pharmaceuticals’ Spravato Support Program for those who qualify.

Take the First Step Toward Healing

If you or a loved one is struggling with treatment-resistant depression or major depressive disorder with suicidal thoughts, Spravato may be the solution you’ve been looking for.

FAQ

While both Spravato and ketamine are derived from the same compound, Spravato is an FDA-approved treatment covered by insurance, while IV ketamine therapy is an off-label treatment. Additionally, Spravato is a nasal spray, whereas ketamine is administered via IV infusion, intramuscular injection, or troches.

Spravato has just gained approval for use as a standalone treatment, which means you do not need to be on any antidepressants to be eligible. However, if you are currently using an SSRI, you can still receive Spravato. 

Most major insurance providers cover Spravato therapy for patients with treatment-resistant depression. Illumma accepts Blue Cross Blue Shield of Texas and UnitedHealthcare.

Each Spravato session lasts approximately two hours to allow for monitoring after administration.

Common side effects include dizziness, dissociation, drowsiness, and nausea. Our medical team will monitor you throughout treatment to ensure safety.

Start Your Healing Journey with Spravato at Illumma